AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in December 2025 (see full year).

Return flights

15 Dec - 07 Jan	Iberia
15 Dec - 13 Jan	Iberia
10 Dec - 31 Dec	Iberia
16 Dec - 18 Jan	Iberia	direct
15 Dec - 11 Jan	Iberia
23 Dec - 06 Jan	Iberia	direct
02 Dec - 31 Jan	Iberia	direct
09 Dec - 31 Jan	Iberia
25 Dec - 12 Jan	Iberia	direct
09 Dec - 31 Jan	LATAM Airlines Group	direct
17 Dec - 07 Jan	Iberia
01 Dec - 08 Dec	Iberia
23 Dec - 30 Dec	LATAM Airlines Group	direct
13 Dec - 28 Dec	Iberia
13 Dec - 28 Dec	Iberia	direct

Also check the deals for one-way flights from Quito to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in December from 640€

Return flights