AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in December 2025 (see full year).

Return flights

25 Dec - 22 Jan	KLM
15 Dec - 21 Jan	Avianca
25 Dec - 22 Jan	Air Europa	direct
18 Dec - 01 Jan	Air Europa	direct
23 Dec - 08 Jan	Air Europa	direct
30 Dec - 24 Jan	Air Europa	direct
13 Dec - 10 Jan	Air Europa	direct
18 Dec - 13 Jan	Air Europa	direct
27 Dec - 31 Jan	Air Europa	direct
24 Dec - 31 Dec	KLM
16 Dec - 31 Dec	KLM
25 Dec - 31 Dec	KLM
23 Dec - 11 Jan	KLM
23 Dec - 30 Dec	Air Europa	direct
16 Dec - 30 Dec	Air Europa	direct
24 Dec - 31 Dec	LATAM Airlines Group	direct
15 Dec - 31 Dec	Avianca
22 Dec - 29 Dec	Iberia
15 Dec - 29 Dec	Iberia
16 Dec - 31 Dec	Iberia	direct

Also check the deals for one-way flights from Quito to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Cheapest return flights from Quito to Madrid in December from 603€

Return flights