AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in December 2025 (see full year).

Return flights

24 Dec - 24 Jan	KLM
25 Dec - 15 Jan	Air Europa	direct
24 Dec - 12 Jan	Iberia
23 Dec - 11 Jan	Iberia
22 Dec - 11 Jan	Iberia
22 Dec - 14 Jan	Iberia
25 Dec - 10 Jan	Air Europa	direct
23 Dec - 14 Jan	Iberia
23 Dec - 13 Jan	Iberia	direct
16 Dec - 08 Jan	Air Europa	direct
24 Dec - 31 Dec	KLM
16 Dec - 30 Dec	Iberia
18 Dec - 31 Dec	Iberia
23 Dec - 30 Dec	Iberia
15 Dec - 29 Dec	Iberia
24 Dec - 31 Dec	Iberia	direct
09 Dec - 15 Dec	Avianca
15 Dec - 27 Dec	Iberia
15 Dec - 26 Dec	Iberia
07 Dec - 08 Dec	Iberia

Also check the deals for one-way flights from Quito to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in December from 640€

Return flights