AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in December 2025 (see full year).

Return flights

05 Dec - 08 Jan	Iberia	direct
17 Dec - 31 Dec	Iberia
18 Dec - 03 Jan	Air Europa	direct
18 Dec - 08 Jan	Air Europa	direct
20 Dec - 03 Jan	Air Europa	direct
23 Dec - 04 Jan	Iberia
22 Dec - 03 Jan	Iberia	direct
27 Dec - 03 Jan	Air Europa	direct
10 Dec - 25 Dec	Iberia
19 Dec - 07 Jan	Iberia
23 Dec - 04 Jan	LATAM Airlines Group	direct
19 Dec - 07 Jan	LATAM Airlines Group	direct
16 Dec - 28 Dec	Iberia	direct
01 Dec - 15 Dec	Iberia

Also check the deals for one-way flights from Quito to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in December from 690€

Return flights