AirHint found the following cheapest one-way flights from Quito (UIO) to Madrid (MAD) in December 2025 (see full year).
One-Way flights
| 25 Dec | Air Europa | direct | |
| 23 Dec | Air Europa | direct | |
| 03 Dec | LATAM Airlines Group | ||
| 04 Dec | Avianca | ||
| 09 Dec | Avianca | ||
| 08 Dec | Avianca | ||
| 05 Dec | Avianca | ||
| 02 Dec | Avianca | ||
| 10 Dec | Avianca | ||
| 07 Dec | LATAM Airlines Group |
Also check the deals for return flights from Quito to Madrid in December.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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