AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Madrid (MAD) in September 2025 (see full year).

Return flights

08 Sep - 15 Sep	Spirit Airlines
18 Sep - 28 Sep	Spirit Airlines
20 Sep - 23 Sep	Arajet
09 Sep - 16 Sep	Spirit Airlines
18 Sep - 28 Sep	WORLD2FLY	direct
05 Sep - 15 Sep	Arajet
04 Sep - 08 Sep	Arajet
17 Sep - 28 Sep	Arajet
18 Sep - 25 Sep	WORLD2FLY	direct
05 Sep - 08 Sep	Arajet
21 Sep - 06 Oct	Iberia	direct
19 Sep - 06 Oct	Air Europa	direct
18 Sep - 01 Oct	Air Europa	direct
25 Sep - 12 Oct	Air Europa	direct
17 Sep - 23 Oct	Air Europa	direct
17 Sep - 30 Oct	Air Europa	direct
20 Sep - 07 Oct	Air Europa	direct
20 Sep - 06 Oct	Air Europa	direct
25 Sep - 16 Oct	Air Europa	direct
23 Sep - 14 Oct	Air Europa	direct

Also check the deals for one-way flights from Santo Domingo to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santo Domingo to Madrid in September from 548€

Return flights