AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

Return flights

14 Dec - 18 Jan	WORLD2FLY	direct
21 Dec - 15 Jan	WORLD2FLY
14 Dec - 17 Jan	WORLD2FLY
21 Dec - 18 Jan	WORLD2FLY	direct
20 Dec - 18 Jan	WORLD2FLY	direct
28 Dec - 18 Jan	WORLD2FLY	direct
30 Dec - 17 Jan	Air Europa	direct
10 Dec - 16 Jan	Air Europa	direct
16 Dec - 15 Jan	Air Europa	direct
15 Dec - 16 Jan	Air Europa	direct
24 Dec - 31 Dec	Air Europa	direct
10 Dec - 12 Dec	Air Europa
14 Dec - 22 Dec	WORLD2FLY
18 Dec - 31 Dec	Air Europa	direct
22 Dec - 23 Dec	Air Europa
08 Dec - 16 Dec	jetBlue
22 Dec - 25 Dec	Air Europa
14 Dec - 21 Dec	WORLD2FLY
10 Dec - 22 Dec	KLM
18 Dec - 28 Dec	Iberia

Also check the deals for one-way flights from Santo Domingo to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santo Domingo to Madrid in December from 593€

Return flights