AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

Return flights

23 Dec - 22 Jan	Iberia	direct
16 Dec - 16 Jan	Air Europa	direct
15 Dec - 16 Jan	Air Europa	direct
05 Dec - 08 Dec	Spirit Airlines
20 Dec - 08 Jan	WORLD2FLY	direct
20 Dec - 04 Jan	WORLD2FLY	direct
21 Dec - 11 Jan	WORLD2FLY	direct
20 Dec - 06 Jan	Iberia	direct
02 Dec - 03 Jan	Iberia	direct
18 Dec - 02 Jan	Iberia	direct
18 Dec - 03 Jan	Iberia	direct
15 Dec - 30 Dec	Iberia
20 Dec - 27 Dec	Iberia
15 Dec - 30 Dec	Air Europa	direct
18 Dec - 29 Dec	Air Europa	direct
20 Dec - 27 Dec	Air Europa	direct
05 Dec - 08 Dec	Air Europa	direct

Also check the deals for one-way flights from Santo Domingo to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santo Domingo to Madrid in December from 603€

Return flights