AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

Return flights

13 Dec - 19 Jan	WORLD2FLY
25 Dec - 01 Jan	WORLD2FLY	direct
20 Dec - 08 Jan	WORLD2FLY	direct
20 Dec - 04 Jan	WORLD2FLY	direct
13 Dec - 19 Jan	Iberia	direct
01 Dec - 15 Dec	Arajet
25 Dec - 02 Jan	Iberia	direct
24 Dec - 06 Jan	Iberia	direct
10 Dec - 10 Jan	Arajet
15 Dec - 31 Dec	Iberia	direct
03 Dec - 10 Dec	KLM
14 Dec - 27 Dec	Iberia
03 Dec - 10 Dec	Air Europa	direct
01 Dec - 15 Dec	Iberia	direct
14 Dec - 27 Dec	Air Europa	direct

Also check the deals for one-way flights from Santo Domingo to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santo Domingo to Madrid in December from 679€

Return flights