Cheapest one-way flights from Santo Domingo to Madrid in December from 322€

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

12 Dec Arajet
14 Dec Arajet
09 Dec Arajet
14 Dec WORLD2FLY direct
31 Dec Arajet
25 Dec WORLD2FLY direct
20 Dec WORLD2FLY direct
12 Dec Air Europa direct
31 Dec Air Europa direct

Also check the deals for return flights from Santo Domingo to Madrid in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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