Cheapest one-way flights from Santo Domingo to Madrid in December from 226€

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

06 Dec WORLD2FLY direct
07 Dec WORLD2FLY direct
13 Dec WORLD2FLY direct
11 Dec WORLD2FLY direct
04 Dec WORLD2FLY direct
23 Dec Air Europa direct
09 Dec Arajet
30 Dec Air Europa direct
10 Dec Arajet
02 Dec Iberia direct

Also check the deals for return flights from Santo Domingo to Madrid in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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