Cheapest one-way flights from Santo Domingo to Madrid in December from 251€

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

07 Dec WORLD2FLY direct
11 Dec WORLD2FLY direct
13 Dec WORLD2FLY direct
04 Dec WORLD2FLY direct
21 Dec WORLD2FLY direct
23 Dec Air Europa direct
24 Dec Air Europa direct
09 Dec Arajet
03 Dec Spirit Airlines
10 Dec Spirit Airlines

Also check the deals for return flights from Santo Domingo to Madrid in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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