Cheapest one-way flights from Santo Domingo to Madrid in December from 353€

Best time to book flights for Santo Domingo (SDQ) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

04 Dec WORLD2FLY direct
11 Dec WORLD2FLY direct
10 Dec Arajet
10 Dec Iberia direct

Also check the deals for return flights from Santo Domingo to Madrid in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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