AirHint found the following cheapest return flights from Santiago (SCL) to Madrid (MAD) in October 2025 (see full year).

Return flights

02 Oct - 22 Oct	Iberia
07 Oct - 07 Nov	Iberia
14 Oct - 03 Nov	Iberia
02 Oct - 03 Nov	Iberia
09 Oct - 22 Oct	Iberia
23 Oct - 10 Nov	Iberia
23 Oct - 03 Nov	Iberia
21 Oct - 03 Nov	Iberia
21 Oct - 02 Nov	Iberia
19 Oct - 03 Nov	LATAM Airlines Group
21 Oct - 27 Oct	Iberia
02 Oct - 24 Oct	Iberia
14 Oct - 27 Oct	Iberia
19 Oct - 29 Oct	LATAM Airlines Group
28 Oct - 15 Nov	LATAM Airlines Group
31 Oct - 15 Nov	LATAM Airlines Group	direct
18 Oct - 29 Oct	LATAM Airlines Group
21 Oct - 28 Oct	LATAM Airlines Group
16 Oct - 28 Oct	LATAM Airlines Group
04 Oct - 24 Oct	Iberia

Also check the deals for one-way flights from Santiago to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Madrid in October from 768€

Return flights