Cheapest one-way flights from Santiago to Madrid in October from 374€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

12 Oct Avianca
06 Oct Avianca
05 Oct Avianca
04 Oct Aerolineas Argentinas
14 Oct Aerolineas Argentinas
16 Oct Aerolineas Argentinas
22 Oct Aerolineas Argentinas
27 Oct Aerolineas Argentinas
23 Oct Aerolineas Argentinas
20 Oct LATAM Airlines Group

Also check the deals for return flights from Santiago to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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