Cheapest one-way flights from Santiago to Madrid in October from 371€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

01 Oct LATAM Airlines Group
09 Oct Avianca
20 Oct Arajet
26 Oct LATAM Airlines Group
25 Oct LATAM Airlines Group
31 Oct LATAM Airlines Group
10 Oct Avianca
21 Oct Avianca
27 Oct Arajet
16 Oct LATAM Airlines Group

Also check the deals for return flights from Santiago to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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