Cheapest return flights from Panama City to Madrid in September from 692€

Best time to book flights for Panama City (PTY) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in September 2025 (see full year).

Return flights

20 Sep - 24 Sep Air Europa direct
14 Sep - 21 Sep Air Europa direct
15 Sep - 26 Sep Iberia direct
08 Sep - 21 Sep Air France
06 Sep - 21 Sep Air France
11 Sep - 29 Sep Air France
18 Sep - 25 Sep Air Europa direct
12 Sep - 28 Sep Air Europa direct
04 Sep - 14 Sep Air Europa direct
09 Sep - 20 Sep Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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