Cheapest return flights from Panama City to Madrid in September from 595€

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in September 2025 (see full year).

Return flights

22 Sep - 13 Oct Air Europa direct
18 Sep - 29 Sep Avianca
16 Sep - 19 Sep Avianca
12 Sep - 19 Sep Air France
06 Sep - 25 Sep Air France
12 Sep - 21 Sep Air France
11 Sep - 19 Sep Air France
26 Sep - 30 Oct Avianca
09 Sep - 29 Sep Air France
10 Sep - 29 Sep Air France
06 Sep - 27 Sep Air France
07 Sep - 27 Sep Air France
14 Sep - 04 Oct Turkish Airlines
13 Sep - 03 Oct Air France
14 Sep - 03 Oct Air France
12 Sep - 03 Oct Air France
11 Sep - 03 Oct Air France
09 Sep - 03 Oct Air France
10 Sep - 03 Oct Air France
06 Sep - 03 Oct Air France

Also check the deals for one-way flights from Panama City to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Feel free to contact us with any feedback or request another flight research.