Cheapest return flights from Panama City to Madrid in September from 650€

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in September 2025 (see full year).

Return flights

24 Sep - 04 Oct Turkish Airlines
24 Sep - 09 Oct Turkish Airlines
28 Sep - 04 Oct Turkish Airlines
30 Sep - 07 Oct Avianca
30 Sep - 14 Oct Avianca
29 Sep - 07 Oct Copa
29 Sep - 26 Oct Copa
24 Sep - 22 Oct Turkish Airlines
21 Sep - 28 Sep KLM
30 Sep - 30 Oct Avianca
30 Sep - 13 Oct Avianca
17 Sep - 26 Sep Iberia
26 Sep - 27 Sep Avianca
18 Sep - 28 Sep Iberia
17 Sep - 30 Sep Iberia
17 Sep - 28 Sep Air France
16 Sep - 28 Sep Avianca
19 Sep - 26 Sep Iberia direct
21 Sep - 28 Sep Air Europa direct
17 Sep - 23 Sep Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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