AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in September 2026 (see full year).
Return flights
| 22 Sep - 29 Sep | Air Europa | direct | |
| 02 Sep - 16 Sep | Iberia | direct | |
| 30 Sep - 07 Oct | Air France | ||
| 01 Sep - 15 Sep | Air Europa | direct | |
| 26 Sep - 09 Oct | Avianca |
Also check the deals for one-way flights from Panama City to Madrid in September.
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