Cheapest return flights from Panama City to Madrid in September from 616€

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in September 2025 (see full year).

Return flights

10 Sep - 16 Sep Air France
12 Sep - 21 Sep Air France
10 Sep - 17 Sep Air France
10 Sep - 25 Sep Air France
30 Sep - 27 Oct Air Europa direct
25 Sep - 30 Oct Air Europa direct
10 Sep - 18 Sep Air France
28 Sep - 30 Oct Air Europa direct
30 Sep - 30 Oct Air Europa direct
25 Sep - 10 Oct Air Europa direct
30 Sep - 13 Oct Air Europa direct
12 Sep - 24 Sep Air France
19 Sep - 27 Sep Turkish Airlines
10 Sep - 24 Sep Air France
12 Sep - 22 Sep Air France
19 Sep - 23 Sep Turkish Airlines
26 Sep - 12 Oct Air France
29 Sep - 06 Oct Air Europa direct
10 Sep - 16 Oct Turkish Airlines
30 Sep - 31 Oct Turkish Airlines

Also check the deals for one-way flights from Panama City to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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