Cheapest one-way flights from Panama City to Madrid in September from 504€

Best time to book flights for Panama City (PTY) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Panama City (PTY) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

20 Sep Air Europa direct
22 Sep Avianca
13 Sep Avianca
16 Sep Avianca
22 Sep Air Europa direct
16 Sep Air Europa direct
13 Sep Air Europa direct
02 Sep Turkish Airlines
01 Sep Turkish Airlines
02 Sep Air Europa direct

Also check the deals for return flights from Panama City to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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