Cheapest return flights from Panama City to Madrid in April from $647

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in April 2026 (see full year).

Return flights

27 Apr - 11 May Air France
27 Apr - 12 May Air France
26 Apr - 17 May Air France
27 Apr - 07 May Air France
26 Apr - 15 May Air France
25 Apr - 16 May Air France
21 Apr - 27 Apr Air France
18 Apr - 26 Apr Air France
14 Apr - 29 Apr Air France
21 Apr - 28 Apr Air France
14 Apr - 28 Apr Air France
30 Apr - 15 May Air France
30 Apr - 19 May Air France
30 Apr - 17 May Air France
23 Apr - 23 May Air France
14 Apr - 23 Apr Air France
19 Apr - 30 Apr Avianca
14 Apr - 18 Apr Avianca
07 Apr - 27 Apr Avianca
14 Apr - 20 Apr Avianca

Also check the deals for one-way flights from Panama City to Madrid in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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