Cheapest one-way flights from Panama City to Madrid in April from 503€

Best time to book flights for Panama City (PTY) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Panama City (PTY) to Madrid (MAD) in April 2025 (see full year).

One-Way flights

09 Apr Air Europa direct
01 Apr Copa
26 Apr Avianca
14 Apr Turkish Airlines
15 Apr Turkish Airlines
21 Apr Air Europa direct
16 Apr Avianca
22 Apr Avianca
16 Apr Air Europa direct
22 Apr Air Europa direct

Also check the deals for return flights from Panama City to Madrid in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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