Cheapest return flights from Panama City to Madrid in December from 611€

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in December 2025 (see full year).

Return flights

24 Dec - 06 Jan KLM
25 Dec - 18 Jan KLM
06 Dec - 13 Dec Turkish Airlines
01 Dec - 31 Dec Air France
01 Dec - 10 Dec Iberia direct
03 Dec - 10 Dec Turkish Airlines
05 Dec - 07 Dec Turkish Airlines
24 Dec - 31 Dec KLM
25 Dec - 05 Jan KLM
14 Dec - 17 Jan Avianca
03 Dec - 10 Dec Iberia direct
01 Dec - 12 Dec Air Europa direct
24 Dec - 07 Jan KLM
06 Dec - 07 Jan Air France
15 Dec - 18 Jan Air France
21 Dec - 06 Jan Air France
27 Dec - 07 Jan Air France
06 Dec - 13 Dec Air Europa direct
18 Dec - 06 Jan KLM
01 Dec - 31 Dec Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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