AirHint found the following cheapest return flights from Palermo (PMO) to Lyon (LYS) in October 2025 (see full year).

Return flights

27 Oct - 31 Oct	easyJet	direct
03 Oct - 10 Oct	Volotea	direct
03 Oct - 05 Oct	Volotea
03 Oct - 07 Oct	Volotea
09 Oct - 10 Oct	Vueling Airlines
24 Oct - 31 Oct	Volotea	direct
03 Oct - 22 Oct	Volotea
03 Oct - 17 Oct	Volotea	direct
09 Oct - 24 Oct	Vueling Airlines
06 Oct - 10 Oct	Vueling Airlines
24 Oct - 01 Nov	Volotea
13 Oct - 01 Nov	Vueling Airlines
27 Oct - 01 Nov	Vueling Airlines
24 Oct - 07 Nov	Volotea
27 Oct - 07 Nov	Vueling Airlines
31 Oct - 01 Nov	Volotea
31 Oct - 07 Nov	Volotea

Also check the deals for one-way flights from Palermo to Lyon in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Lyon in October from 111€

Return flights