AirHint found the following cheapest one-way flights from Palermo (PMO) to Lyon (LYS) in October 2025 (see full year).

One-Way flights

11 Oct	easyJet	direct
04 Oct	easyJet	direct
08 Oct	easyJet	direct
18 Oct	easyJet	direct
15 Oct	easyJet	direct
10 Oct	Volotea	direct
13 Oct	Transavia France	direct
22 Oct	easyJet	direct
07 Oct	Ryanair
21 Oct	Aeroitalia

Also check the deals for return flights from Palermo to Lyon in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Palermo to Lyon in October from 27€

One-Way flights