AirHint found the following cheapest return flights from Miami (MIA) to Santiago (SCL) in October 2025 (see full year).

Return flights

02 Oct - 12 Oct	Arajet
23 Oct - 04 Nov	Arajet
09 Oct - 16 Oct	Arajet
14 Oct - 17 Oct	Arajet
21 Oct - 23 Oct	Arajet
10 Oct - 17 Oct	Sky Airline
12 Oct - 19 Oct	Sky Airline
13 Oct - 20 Oct	Sky Airline
15 Oct - 22 Oct	Avianca
20 Oct - 27 Oct	Avianca
21 Oct - 28 Oct	Arajet
31 Oct - 03 Nov	Avianca
28 Oct - 25 Nov	Copa
23 Oct - 04 Nov	Delta	direct
31 Oct - 03 Nov	LATAM Airlines Group	direct

Also check the deals for one-way flights from Miami to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Miami to Santiago in October from 382€

Return flights