AirHint found the following cheapest one-way flights from Miami (MIA) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

02 Oct	Arajet
14 Oct	Arajet
20 Oct	Sky Airline
24 Oct	Sky Airline
19 Oct	Avianca
20 Oct	LATAM Airlines Group	direct
02 Oct	Delta	direct
14 Oct	Delta	direct
24 Oct	LATAM Airlines Group	direct
03 Oct	Copa

Also check the deals for return flights from Miami to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Miami to Santiago in October from 184€

One-Way flights