Cheapest return flights from Mexico City to Santiago in December from 390€

Best time to book flights for Mexico City (MEX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in December 2025 (see full year).

Return flights

09 Dec - 17 Dec Arajet
02 Dec - 10 Dec Arajet
30 Dec - 07 Jan Arajet
23 Dec - 07 Jan Arajet
23 Dec - 31 Dec Arajet
21 Dec - 31 Dec Arajet
04 Dec - 12 Dec Arajet
23 Dec - 05 Jan Arajet
18 Dec - 27 Dec Arajet
02 Dec - 17 Dec LATAM Airlines Group
12 Dec - 26 Dec LATAM Airlines Group direct
28 Dec - 13 Jan LATAM Airlines Group
21 Dec - 02 Jan Arajet
05 Dec - 21 Dec LATAM Airlines Group
02 Dec - 17 Dec Aeromexico direct
17 Dec - 01 Jan LATAM Airlines Group
26 Dec - 10 Jan LATAM Airlines Group direct
20 Dec - 04 Jan Viva Aerobus
25 Dec - 03 Jan LATAM Airlines Group
14 Dec - 05 Jan LATAM Airlines Group

Also check the deals for one-way flights from Mexico City to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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