Cheapest return flights from Mexico City to Santiago in December from 461€

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in December 2025 (see full year).

Return flights

08 Dec - 17 Dec Aeromexico direct
08 Dec - 16 Dec Aeromexico direct
08 Dec - 22 Jan Aeromexico direct
09 Dec - 16 Dec LATAM Airlines Group
16 Dec - 23 Dec LATAM Airlines Group direct
01 Dec - 08 Dec Copa
02 Dec - 10 Dec Copa
10 Dec - 17 Dec LATAM Airlines Group direct
15 Dec - 26 Dec LATAM Airlines Group direct
15 Dec - 23 Dec LATAM Airlines Group direct
03 Dec - 24 Dec LATAM Airlines Group
12 Dec - 20 Jan Copa
21 Dec - 01 Jan LATAM Airlines Group direct
25 Dec - 26 Jan Copa
17 Dec - 15 Jan Avianca
25 Dec - 26 Jan LATAM Airlines Group direct
26 Dec - 26 Jan LATAM Airlines Group
29 Dec - 15 Jan Avianca
04 Dec - 08 Jan Arajet
25 Dec - 02 Jan LATAM Airlines Group

Also check the deals for one-way flights from Mexico City to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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