Cheapest return flights from Mexico City to Santiago in December from 459€

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in December 2025 (see full year).

Return flights

02 Dec - 09 Dec Avianca
02 Dec - 10 Dec LATAM Airlines Group
10 Dec - 23 Dec LATAM Airlines Group
01 Dec - 10 Dec LATAM Airlines Group
15 Dec - 26 Dec LATAM Airlines Group
09 Dec - 23 Dec LATAM Airlines Group
15 Dec - 26 Dec LATAM Airlines Group direct
10 Dec - 23 Dec LATAM Airlines Group direct
10 Dec - 17 Dec LATAM Airlines Group direct
09 Dec - 23 Dec LATAM Airlines Group direct
31 Dec - 17 Jan LATAM Airlines Group
26 Dec - 30 Jan LATAM Airlines Group direct
31 Dec - 17 Jan LATAM Airlines Group direct
31 Dec - 14 Jan Aeromexico direct
22 Dec - 22 Jan Avianca
22 Dec - 17 Jan Avianca
07 Dec - 06 Jan Avianca
24 Dec - 01 Jan LATAM Airlines Group
14 Dec - 01 Jan Copa
15 Dec - 09 Jan LATAM Airlines Group

Also check the deals for one-way flights from Mexico City to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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