Cheapest return flights from Mexico City to Santiago in December from 450€

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in December 2025 (see full year).

Return flights

07 Dec - 16 Dec Avianca
01 Dec - 08 Dec Avianca
01 Dec - 05 Dec Avianca
16 Dec - 22 Jan Avianca
02 Dec - 09 Dec Avianca
02 Dec - 16 Dec Avianca
02 Dec - 22 Jan Avianca
04 Dec - 15 Dec Volaris
19 Dec - 13 Jan Avianca
01 Dec - 07 Dec Avianca
01 Dec - 10 Dec LATAM Airlines Group
02 Dec - 10 Dec Copa
09 Dec - 23 Dec LATAM Airlines Group direct
02 Dec - 22 Jan Aeromexico direct
25 Dec - 06 Jan Avianca
18 Dec - 08 Jan Avianca
26 Dec - 08 Jan Avianca
18 Dec - 06 Jan Avianca
22 Dec - 06 Jan Avianca
19 Dec - 06 Jan Avianca

Also check the deals for one-way flights from Mexico City to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Feel free to contact us with any feedback or request another flight research.