AirHint found the following cheapest one-way flights from Mexico City (MEX) to Santiago (SCL) in December 2025 (see full year).
One-Way flights
| 04 Dec | Arajet | ||
| 03 Dec | Avianca | ||
| 05 Dec | Avianca | ||
| 09 Dec | Avianca | ||
| 07 Dec | Avianca | ||
| 06 Dec | Avianca | ||
| 31 Dec | Avianca | ||
| 08 Dec | Avianca | ||
| 02 Dec | Avianca | ||
| 24 Dec | Copa |
Also check the deals for return flights from Mexico City to Santiago in December.
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