Cheapest one-way flights from Mexico City to Santiago in December from 246€

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

24 Dec Avianca
08 Dec Avianca
03 Dec Avianca
15 Dec Avianca
05 Dec Avianca
17 Dec Avianca
08 Dec LATAM Airlines Group direct
03 Dec LATAM Airlines Group direct
02 Dec LATAM Airlines Group direct
05 Dec LATAM Airlines Group direct

Also check the deals for return flights from Mexico City to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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