Cheapest return flights from Mexico City to Santiago in October from 450€

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in October 2025 (see full year).

Return flights

31 Oct - 10 Nov Avianca
29 Oct - 11 Nov Avianca
13 Oct - 20 Oct Volaris
01 Oct - 07 Oct Arajet
18 Oct - 28 Oct Avianca
18 Oct - 12 Nov Avianca
23 Oct - 06 Nov Avianca
18 Oct - 13 Nov Avianca
02 Oct - 28 Oct Avianca
03 Oct - 28 Oct Avianca
14 Oct - 28 Oct Avianca
21 Oct - 03 Nov Avianca
17 Oct - 04 Nov Avianca
02 Oct - 09 Oct Copa
06 Oct - 13 Oct Copa
01 Oct - 08 Oct Copa
24 Oct - 01 Nov Avianca
01 Oct - 14 Oct Copa
25 Oct - 01 Nov Avianca
23 Oct - 01 Nov Avianca

Also check the deals for one-way flights from Mexico City to Santiago in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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