Cheapest return flights from Mexico City to Santiago in October from 454€

Best time to book flights for Mexico City (MEX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in October 2025 (see full year).

Return flights

01 Oct - 15 Oct Avianca
03 Oct - 18 Oct Avianca
04 Oct - 18 Oct Avianca
04 Oct - 25 Oct Avianca
24 Oct - 08 Nov Avianca
05 Oct - 18 Oct Avianca
12 Oct - 25 Oct Avianca
13 Oct - 25 Oct Avianca
14 Oct - 25 Oct Avianca
05 Oct - 14 Oct Avianca
01 Oct - 15 Oct LATAM Airlines Group direct

Also check the deals for one-way flights from Mexico City to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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