Cheapest one-way flights from Mexico City to Santiago in October from 289€

Best time to book flights for Mexico City (MEX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

20 Oct Avianca
17 Oct Avianca
01 Oct Avianca
18 Oct Avianca
27 Oct Avianca
07 Oct Avianca
01 Oct LATAM Airlines Group direct
27 Oct LATAM Airlines Group direct
18 Oct LATAM Airlines Group direct
20 Oct LATAM Airlines Group direct

Also check the deals for return flights from Mexico City to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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