Cheapest return flights from Mexico City to Panama City in December from 278€

AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in December 2025 (see full year).

Return flights

15 Dec - 27 Dec Avianca
30 Dec - 15 Jan Aeromexico direct
17 Dec - 28 Dec Aeromexico direct
15 Dec - 22 Dec Aeromexico direct
12 Dec - 23 Dec Aeromexico direct
13 Dec - 27 Dec Aeromexico direct
14 Dec - 27 Dec Aeromexico direct
15 Dec - 27 Dec Aeromexico direct
16 Dec - 27 Dec Aeromexico direct
17 Dec - 27 Dec Aeromexico direct
18 Dec - 27 Dec Aeromexico direct
01 Dec - 10 Jan Avianca
01 Dec - 10 Jan Copa direct
27 Dec - 04 Jan Copa direct
25 Dec - 03 Jan Copa direct
30 Dec - 03 Jan Avianca
24 Dec - 02 Jan Viva

Also check the deals for one-way flights from Mexico City to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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