AirHint found the following cheapest one-way flights from Mexico City (MEX) to Panama City (PTY) in December 2025 (see full year).
One-Way flights
| 31 Dec | Aeromexico | direct | |
| 02 Dec | Avianca | ||
| 09 Dec | Avianca | ||
| 04 Dec | Avianca | ||
| 08 Dec | Avianca | ||
| 06 Dec | Avianca | ||
| 11 Dec | Avianca | ||
| 30 Dec | Copa | direct | |
| 24 Dec | Aeromexico | ||
| 01 Dec | Avianca |
Also check the deals for return flights from Mexico City to Panama City in December.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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