Cheapest one-way flights from Mexico City to Panama City in December from 136€

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Panama City (PTY) in December 2025 (see full year).

One-Way flights

30 Dec Aeromexico direct
11 Dec Avianca
13 Dec Avianca
09 Dec Avianca
05 Dec Avianca
06 Dec Avianca
20 Dec Avianca
03 Dec Avianca
08 Dec Avianca
12 Dec Avianca

Also check the deals for return flights from Mexico City to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Feel free to contact us with any feedback or request another flight research.