AirHint found the following cheapest return flights from Chicago (MDW) to Rome (FCO) in April 2026 (see full year).

Return flights

16 Apr - 20 Apr	Air France
22 Apr - 02 May	Delta
11 Apr - 21 Apr	Delta
23 Apr - 28 Apr	Delta
23 Apr - 29 Apr	Delta
23 Apr - 01 May	Air France
23 Apr - 08 May	Delta
23 Apr - 30 Apr	Delta
11 Apr - 18 Apr	Delta
14 Apr - 20 Apr	Delta
23 Apr - 27 Apr	Delta
23 Apr - 02 May	Delta
23 Apr - 10 May	Delta
24 Apr - 05 May	Delta
13 Apr - 17 Apr	Air France
08 Apr - 14 Apr	Air France
24 Apr - 04 May	Delta
23 Apr - 09 May	Delta
24 Apr - 09 May	Delta
24 Apr - 11 May	Delta

Also check the deals for one-way flights from Chicago to Rome in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome

Cheapest return flights from Chicago to Rome in April from 513€

Return flights