Cheapest return flights from Madrid to Santa Cruz in September from 822€

Best time to book flights for Madrid (MAD) to Santa Cruz (VVI) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santa Cruz (VVI) in September 2025 (see full year).

Return flights

17 Sep - 09 Oct Air Europa direct
23 Sep - 19 Oct LATAM Airlines Group
05 Sep - 30 Sep Air Europa direct
07 Sep - 23 Sep Air Europa direct
01 Sep - 29 Sep Air Europa direct
15 Sep - 29 Sep Air Europa direct
08 Sep - 22 Sep Air Europa direct
02 Sep - 30 Sep LATAM Airlines Group
03 Sep - 16 Sep Air Europa direct
01 Sep - 30 Sep Avianca
09 Sep - 23 Sep Avianca
06 Sep - 27 Sep Avianca
05 Sep - 10 Oct Avianca

Also check the deals for one-way flights from Madrid to Santa Cruz in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santa Cruz

Cheap car rent in Santa Cruz