AirHint found the following cheapest return flights from Madrid (MAD) to Santa Cruz (VVI) in May 2026 (see full year).

Return flights

04 May - 29 May	Avianca
17 May - 25 May	Avianca
01 May - 29 May	Avianca
01 May - 23 May	Avianca
25 May - 29 Jun	Air Europa	direct
15 May - 28 May	Iberia	direct
17 May - 25 May	Iberia	direct
01 May - 23 May	Iberia	direct
10 May - 23 May	Iberia	direct
24 May - 06 Jun	Iberia	direct
27 May - 06 Jun	Iberia	direct
01 May - 13 Jun	Iberia	direct
17 May - 18 Jun	Iberia	direct
01 May - 31 May	Avianca
22 May - 30 May	Avianca
08 May - 04 Jun	Iberia	direct
22 May - 23 Jun	Iberia	direct
20 May - 06 Jun	Air Europa	direct
26 May - 05 Jun	LATAM Airlines Group

Also check the deals for one-way flights from Madrid to Santa Cruz in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santa Cruz in May from 687€

Return flights