AirHint found the following cheapest return flights from Madrid (MAD) to Santa Cruz (VVI) in May 2026 (see full year).

Return flights

09 May - 23 May	Avianca
08 May - 22 May	Avianca
08 May - 21 May	Avianca
13 May - 25 May	Avianca
09 May - 16 May	Avianca
06 May - 16 May	Avianca
13 May - 31 May	Avianca
16 May - 31 May	Avianca
27 May - 23 Jun	Air Europa	direct
30 May - 16 Jun	Air Europa	direct
15 May - 02 Jun	Iberia	direct
06 May - 16 May	Iberia	direct
13 May - 25 May	Iberia	direct
25 May - 10 Jun	LATAM Airlines Group

Also check the deals for one-way flights from Madrid to Santa Cruz in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santa Cruz in May from 514€

Return flights