AirHint found the following cheapest return flights from Madrid (MAD) to Santa Cruz (VVI) in May 2026 (see full year).

Return flights

07 May - 23 May	Avianca
07 May - 21 May	Avianca
07 May - 22 May	Avianca
07 May - 24 May	Avianca
07 May - 19 May	Avianca
05 May - 22 May	Avianca
06 May - 23 May	Avianca
11 May - 20 May	Avianca
06 May - 22 May	Avianca
09 May - 25 May	Avianca
11 May - 09 Jun	Avianca
18 May - 02 Jun	Avianca
29 May - 16 Jun	Avianca
08 May - 04 Jun	Avianca
22 May - 06 Jun	Avianca
20 May - 10 Jun	Avianca
15 May - 04 Jun	Avianca
23 May - 14 Jun	Avianca
29 May - 16 Jun	Iberia	direct
22 May - 06 Jun	Iberia	direct

Also check the deals for one-way flights from Madrid to Santa Cruz in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santa Cruz in May from 521€

Return flights