Cheapest return flights from Madrid to Panama City in September from 713€

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in September 2025 (see full year).

Return flights

11 Sep - 03 Oct KLM
01 Sep - 14 Sep Air Europa direct
26 Sep - 28 Sep Air Europa direct
13 Sep - 27 Sep Air Europa direct
01 Sep - 10 Sep Air Europa direct
01 Sep - 07 Sep Air France
01 Sep - 07 Sep Air Europa direct
11 Sep - 03 Oct Iberia direct

Also check the deals for one-way flights from Madrid to Panama City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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