Cheapest return flights from Madrid to Panama City in May from 539€

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in May 2026 (see full year).

Return flights

01 May - 11 May Avianca
01 May - 12 May Avianca
07 May - 11 May Avianca
06 May - 12 May Avianca
16 May - 29 May Air Europa direct
03 May - 10 May Air Europa direct
13 May - 09 Jun Avianca
13 May - 22 May Air Europa direct
06 May - 24 May Air Europa direct
05 May - 19 May Avianca
15 May - 24 May Avianca
30 May - 11 Jun Air Europa direct
22 May - 23 Jun Air Europa direct
30 May - 07 Jun Air Europa direct
28 May - 11 Jun Air Europa direct
25 May - 07 Jun Air Europa direct
18 May - 08 Jun Air Europa direct
29 May - 08 Jun Air Europa direct
29 May - 07 Jun Iberia direct
15 May - 15 Jun Air Europa direct

Also check the deals for one-way flights from Madrid to Panama City in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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