Cheapest one-way flights from Madrid to Panama City in May from 366€

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Panama City (PTY) in May 2025 (see full year).

One-Way flights

18 May Air Europa direct
12 May Air Europa direct
02 May Air Europa direct
31 May Air Europa direct
06 May Air Europa direct
26 May Air Europa direct
21 May Air Europa direct
09 May Air Europa direct
11 May Air Europa direct
04 May Air Europa direct

Also check the deals for return flights from Madrid to Panama City in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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