Cheapest return flights from Madrid to Panama City in December from 677€

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in December 2025 (see full year).

Return flights

02 Dec - 15 Dec Wizz Air Malta
07 Dec - 15 Dec Wizz Air Malta
01 Dec - 07 Dec Air France
05 Dec - 13 Dec Ryanair
01 Dec - 08 Dec Air France
05 Dec - 15 Dec Ryanair
04 Dec - 09 Dec Air France
03 Dec - 09 Dec Air France
07 Dec - 22 Dec Ryanair
09 Dec - 20 Dec Ryanair
11 Dec - 23 Jan Wizz Air Malta
14 Dec - 15 Jan Wizz Air Malta
15 Dec - 15 Jan United
05 Dec - 14 Jan United
16 Dec - 15 Jan United
05 Dec - 12 Jan United
12 Dec - 31 Jan United
16 Dec - 11 Jan United
13 Dec - 30 Jan United
14 Dec - 31 Jan United

Also check the deals for one-way flights from Madrid to Panama City in December.

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