Cheapest return flights from Madrid to Panama City in October from 716€
AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in October 2025 (see full year).
Return flights
| 04 Oct - 11 Oct | Air Europa | direct | |
| 06 Oct - 19 Oct | Air Europa | direct | |
| 03 Oct - 03 Nov | Air Europa | direct |
Also check the deals for one-way flights from Madrid to Panama City in October.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
