Cheapest return flights from Madrid to Panama City in October from 511€

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in October 2025 (see full year).

Return flights

10 Oct - 25 Nov Avianca
09 Oct - 25 Nov Avianca
28 Oct - 08 Nov Air Europa direct
21 Oct - 26 Oct Air Europa direct
09 Oct - 12 Oct Air France
24 Oct - 28 Oct Air Europa direct
07 Oct - 14 Oct Iberia direct
09 Oct - 16 Oct Iberia direct
07 Oct - 18 Oct Iberia direct
26 Oct - 02 Nov Air Europa direct
25 Oct - 03 Nov Air Europa direct
24 Oct - 02 Nov Air Europa direct
31 Oct - 08 Nov Air Europa direct
27 Oct - 05 Nov Iberia direct
28 Oct - 04 Nov Air Europa direct
30 Oct - 10 Nov Air Europa direct
13 Oct - 14 Oct Air Europa direct
07 Oct - 21 Oct Air Europa direct
26 Oct - 30 Oct Air Europa direct
13 Oct - 26 Oct Air Europa direct

Also check the deals for one-way flights from Madrid to Panama City in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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