Cheapest return flights from Madrid to Panama City in October from 717€

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in October 2025 (see full year).

Return flights

06 Oct - 12 Oct Air Europa direct
04 Oct - 18 Oct Air Europa direct
15 Oct - 09 Nov Air Europa direct
09 Oct - 12 Oct KLM
04 Oct - 04 Oct Avianca
04 Oct - 04 Oct Iberia direct
09 Oct - 12 Oct Iberia direct

Also check the deals for one-way flights from Madrid to Panama City in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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