AirHint found the following cheapest one-way flights from Madrid (MAD) to Panama City (PTY) in October 2025 (see full year).
One-Way flights
| 20 Oct | Iberia | direct | |
| 18 Oct | Iberia | direct | |
| 29 Oct | TAP | ||
| 28 Oct | Ryanair | ||
| 23 Oct | Iberia | direct | |
| 27 Oct | Iberia | ||
| 22 Oct | Avianca | ||
| 21 Oct | Avianca | ||
| 19 Oct | Avianca | ||
| 24 Oct | Avianca |
Also check the deals for return flights from Madrid to Panama City in October.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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