AirHint found the following cheapest return flights from Madrid (MAD) to Prague (PRG) in May 2026 (see full year).

Return flights

21 May - 24 May	ITA Airways
14 May - 17 May	ITA Airways
15 May - 18 May	Air Europa
05 May - 08 May	Iberia
15 May - 17 May	Air Europa
30 May - 01 Jun	Iberia
01 May - 03 May	Air Europa
01 May - 04 May	Smart Wings	direct
01 May - 03 May	Smart Wings	direct
15 May - 18 May	Smart Wings	direct
14 May - 17 May	Smart Wings	direct
30 May - 01 Jun	Smart Wings	direct

Also check the deals for one-way flights from Madrid to Prague in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Prague in May from 162€

Return flights