AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in May 2026 (see full year).

One-Way flights

29 May	Iberia	direct
10 May	Iberia	direct
23 May	Iberia	direct
22 May	Iberia	direct
27 May	Iberia	direct
21 May	Iberia
02 May	Iberia
15 May	Air Europa
15 May	Smart Wings	direct
02 May	Smart Wings	direct

Also check the deals for return flights from Madrid to Prague in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Madrid to Prague in May from 59€

One-Way flights