Cheapest return flights from Madrid to Istanbul in December from 172€

AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in December 2026 (see full year).

Return flights

28 Dec - 06 Jan Air Serbia
06 Dec - 13 Dec Air Serbia
05 Dec - 09 Dec Air Serbia
31 Dec - 04 Jan Air Serbia
04 Dec - 09 Dec Wizz Air UK
09 Dec - 12 Dec Air Serbia
21 Dec - 06 Jan Air Serbia
01 Dec - 16 Dec Lufthansa
19 Dec - 22 Dec Air Serbia
05 Dec - 08 Dec Air Serbia
28 Dec - 03 Jan Air Serbia
01 Dec - 19 Dec Iberia Express
04 Dec - 08 Dec Wizz Air UK
26 Dec - 03 Jan Air Serbia
18 Dec - 10 Jan Air Europa direct
22 Dec - 27 Dec TAROM
22 Dec - 02 Jan Aegean Airlines
26 Dec - 03 Jan Air Europa direct
21 Dec - 06 Jan Air Europa direct
22 Dec - 02 Jan Air Europa direct

Also check the deals for one-way flights from Madrid to Istanbul in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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