Cheapest one-way flights from Madrid to Istanbul in December from 91€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Istanbul (IST) in December 2026 (see full year).

One-Way flights

19 Dec Air Serbia
13 Dec Air Serbia
17 Dec Air Serbia
09 Dec Scandinavian Airlines
09 Dec Air Europa direct
13 Dec Air Europa direct
17 Dec Air Europa direct
19 Dec Air Europa direct
18 Dec SKY express
28 Dec SKY express

Also check the deals for return flights from Madrid to Istanbul in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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