AirHint found the following cheapest return flights from Madrid (MAD) to Guayaquil (GYE) in April 2026 (see full year).

Return flights

24 Apr - 13 May	Avianca
09 Apr - 26 Apr	Avianca
13 Apr - 25 Apr	Avianca
09 Apr - 17 Apr	Avianca
15 Apr - 29 Apr	Avianca
17 Apr - 17 May	Avianca
14 Apr - 13 May	Avianca
30 Apr - 13 May	Avianca
16 Apr - 03 May	Avianca
24 Apr - 10 May	Avianca
23 Apr - 03 May	Avianca
23 Apr - 14 May	Avianca
01 Apr - 30 Apr	LATAM Airlines Group	direct
09 Apr - 23 Apr	LATAM Airlines Group
02 Apr - 18 Apr	Avianca
01 Apr - 22 Apr	LATAM Airlines Group	direct
15 Apr - 29 Apr	LATAM Airlines Group	direct
07 Apr - 16 Apr	LATAM Airlines Group
24 Apr - 13 May	Air Europa	direct
23 Apr - 14 May	Iberia	direct

Also check the deals for one-way flights from Madrid to Guayaquil in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Guayaquil in April from 552€

Return flights