Cheapest one-way flights from Madrid to Guayaquil in April from 328€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Guayaquil (GYE) in April 2026 (see full year).

One-Way flights

22 Apr Air Europa direct
17 Apr Air Europa direct
02 Apr Iberia direct
19 Apr Iberia direct
21 Apr jetBlue
08 Apr Iberia direct
15 Apr Iberia direct
30 Apr Iberia direct
04 Apr LATAM Airlines Group
13 Apr LATAM Airlines Group

Also check the deals for return flights from Madrid to Guayaquil in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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