AirHint found the following cheapest return flights from Madrid (MAD) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

04 Oct - 23 Oct	Turkish Airlines
24 Oct - 28 Nov	Delta
24 Oct - 16 Nov	Delta
01 Oct - 20 Oct	Turkish Airlines
25 Oct - 16 Nov	Royal Air Maroc
05 Oct - 24 Oct	Royal Air Maroc
07 Oct - 19 Oct	Delta
06 Oct - 20 Oct	Delta
07 Oct - 21 Oct	Delta
08 Oct - 22 Oct	Delta
08 Oct - 18 Oct	Delta
13 Oct - 29 Oct	Delta
10 Oct - 27 Oct	Delta
23 Oct - 06 Nov	Delta
23 Oct - 10 Nov	Delta
01 Oct - 06 Nov	Delta
31 Oct - 09 Nov	Royal Air Maroc
29 Oct - 10 Nov	Delta
22 Oct - 27 Nov	Delta
29 Oct - 15 Nov	Delta

Also check the deals for one-way flights from Madrid to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Sao Paulo in October from 604€

Return flights