AirHint found the following cheapest return flights from Madrid (MAD) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

06 Oct - 30 Oct	Avianca
06 Oct - 31 Oct	Avianca
06 Oct - 03 Nov	Avianca
06 Oct - 02 Nov	Avianca
09 Oct - 02 Nov	Avianca
09 Oct - 05 Nov	Avianca
09 Oct - 03 Nov	Avianca
09 Oct - 04 Nov	Avianca
22 Oct - 28 Oct	Delta
02 Oct - 25 Oct	Delta
03 Oct - 12 Oct	Delta
21 Oct - 28 Oct	Delta
08 Oct - 20 Oct	Delta
02 Oct - 16 Oct	Delta
02 Oct - 23 Oct	Delta
08 Oct - 16 Oct	Delta
08 Oct - 01 Nov	Delta
27 Oct - 16 Nov	Delta
08 Oct - 03 Nov	Delta
29 Oct - 30 Nov	Delta

Also check the deals for one-way flights from Madrid to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo

Cheapest return flights from Madrid to Sao Paulo in October from 609€

Return flights