AirHint found the following cheapest return flights from Madrid (MAD) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

25 Oct - 16 Nov	Royal Air Maroc
06 Oct - 27 Oct	TAP
10 Oct - 03 Nov	TAP
07 Oct - 19 Oct	Delta
02 Oct - 28 Oct	Delta
27 Oct - 17 Nov	Delta
27 Oct - 11 Nov	Royal Air Maroc
25 Oct - 02 Nov	Royal Air Maroc
31 Oct - 21 Nov	Royal Air Maroc
20 Oct - 31 Oct	TAP
18 Oct - 25 Oct	TAP
16 Oct - 19 Oct	TAP
23 Oct - 19 Nov	TAP
07 Oct - 14 Oct	Delta
02 Oct - 23 Oct	Delta
25 Oct - 23 Nov	Delta
09 Oct - 20 Oct	Delta
06 Oct - 19 Oct	Delta
20 Oct - 09 Nov	TAP
28 Oct - 14 Nov	Delta

Also check the deals for one-way flights from Madrid to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Sao Paulo in October from 551€

Return flights