AirHint found the following cheapest one-way flights from Madrid (MAD) to Sao Paulo (GRU) in October 2026 (see full year).

One-Way flights

17 Oct	Royal Air Maroc
16 Oct	Royal Air Maroc
29 Oct	Royal Air Maroc
25 Oct	Royal Air Maroc
19 Oct	Royal Air Maroc
26 Oct	Royal Air Maroc
04 Oct	Ryanair
02 Oct	Azul Airlines
30 Oct	Avianca
03 Oct	Air Europa	direct

Also check the deals for return flights from Madrid to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Madrid to Sao Paulo in October from 401€

One-Way flights