AirHint found the following cheapest return flights from Santorini (Thira) (JTR) to Prague (PRG) in September 2025 (see full year).

Return flights

16 Sep - 19 Sep	Ryanair
19 Sep - 22 Sep	Smart Wings
05 Sep - 09 Sep	Ryanair
16 Sep - 19 Sep	Smart Wings	direct
10 Sep - 22 Sep	SKY express
10 Sep - 29 Sep	SKY express
03 Sep - 22 Sep	SKY express
26 Sep - 29 Sep	SKY express
24 Sep - 29 Sep	SKY express
27 Sep - 29 Sep	SKY express
26 Sep - 17 Oct	SKY express
27 Sep - 17 Oct	SKY express
26 Sep - 10 Oct	SKY express
24 Sep - 10 Oct	SKY express
27 Sep - 10 Oct	SKY express
19 Sep - 10 Oct	SKY express
20 Sep - 10 Oct	SKY express
22 Sep - 10 Oct	SKY express

Also check the deals for one-way flights from Santorini (Thira) to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santorini (Thira) to Prague in September from 204€

Return flights