AirHint found the following cheapest return flights from Guayaquil (GYE) to Madrid (MAD) in December 2025 (see full year).

Return flights

24 Dec - 14 Jan	Iberia	direct
12 Dec - 17 Jan	Iberia
10 Dec - 17 Jan	Iberia
08 Dec - 17 Jan	Iberia
06 Dec - 17 Jan	Iberia
07 Dec - 17 Jan	Iberia
21 Dec - 07 Jan	Air Europa	direct
26 Dec - 09 Jan	Air Europa	direct
12 Dec - 07 Jan	Air Europa	direct
22 Dec - 19 Jan	Iberia	direct
12 Dec - 24 Dec	LATAM Airlines Group
01 Dec - 10 Dec	Avianca
22 Dec - 30 Dec	Avianca
05 Dec - 14 Dec	Spirit Airlines
06 Dec - 13 Dec	Spirit Airlines
12 Dec - 24 Dec	Air Europa	direct
08 Dec - 14 Dec	Avianca
05 Dec - 14 Dec	Air Europa	direct

Also check the deals for one-way flights from Guayaquil to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Madrid in December from 619€

Return flights