AirHint found the following cheapest return flights from Guayaquil (GYE) to Madrid (MAD) in December 2025 (see full year).

Return flights

17 Dec - 21 Jan	Iberia	direct
17 Dec - 07 Jan	Iberia	direct
21 Dec - 02 Jan	Air Europa	direct
19 Dec - 04 Jan	Air Europa	direct
20 Dec - 05 Jan	Avianca
28 Dec - 11 Jan	Air Europa	direct
08 Dec - 26 Dec	Avianca
08 Dec - 15 Dec	LATAM Airlines Group
27 Dec - 10 Jan	Avianca
20 Dec - 03 Jan	Avianca

Also check the deals for one-way flights from Guayaquil to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Madrid in December from 710€

Return flights