AirHint found the following cheapest return flights from Guayaquil (GYE) to Madrid (MAD) in December 2025 (see full year).

Return flights

10 Dec - 14 Jan	Air Europa	direct
17 Dec - 14 Jan	Air Europa	direct
17 Dec - 07 Jan	Iberia	direct
17 Dec - 21 Jan	Iberia	direct
17 Dec - 16 Jan	Iberia	direct
26 Dec - 09 Jan	Iberia	direct
17 Dec - 05 Jan	Iberia	direct
17 Dec - 31 Dec	LATAM Airlines Group
17 Dec - 11 Jan	Air Europa	direct
16 Dec - 02 Jan	Iberia
16 Dec - 16 Jan	Iberia
21 Dec - 29 Dec	Avianca
17 Dec - 31 Dec	Air Europa	direct
20 Dec - 28 Dec	Avianca

Also check the deals for one-way flights from Guayaquil to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Madrid in December from 677€

Return flights