AirHint found the following cheapest return flights from Guayaquil (GYE) to Madrid (MAD) in December 2025 (see full year).

Return flights

12 Dec - 21 Jan	KLM
12 Dec - 21 Jan	Air Europa	direct
10 Dec - 13 Jan	KLM
12 Dec - 09 Jan	Air Europa	direct
31 Dec - 11 Jan	Air Europa	direct
24 Dec - 12 Jan	Air Europa
17 Dec - 07 Jan	Air Europa	direct
26 Dec - 07 Jan	Air Europa	direct
19 Dec - 09 Jan	Air Europa	direct
12 Dec - 02 Jan	Air Europa	direct
02 Dec - 31 Dec	LATAM Airlines Group
01 Dec - 25 Dec	Avianca
10 Dec - 24 Dec	KLM
22 Dec - 30 Dec	LATAM Airlines Group
12 Dec - 24 Dec	KLM
16 Dec - 25 Dec	Avianca
08 Dec - 14 Dec	Avianca
22 Dec - 25 Dec	Avianca
08 Dec - 18 Dec	Spirit Airlines
21 Dec - 24 Dec	Air Europa	direct

Also check the deals for one-way flights from Guayaquil to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Madrid in December from 569€

Return flights