AirHint found the following cheapest return flights from Guayaquil (GYE) to Madrid (MAD) in December 2025 (see full year).

Return flights

22 Dec - 21 Jan	Iberia	direct
17 Dec - 14 Jan	Iberia	direct
26 Dec - 14 Jan	Iberia	direct
17 Dec - 21 Jan	Iberia	direct
24 Dec - 31 Dec	LATAM Airlines Group
24 Dec - 11 Jan	Air Europa	direct
24 Dec - 09 Jan	Air Europa	direct
05 Dec - 09 Jan	Iberia	direct
24 Dec - 12 Jan	Air Europa
03 Dec - 10 Dec	Iberia
15 Dec - 31 Dec	LATAM Airlines Group
24 Dec - 31 Dec	Iberia	direct
15 Dec - 31 Dec	Iberia	direct
26 Dec - 12 Jan	Air Europa
19 Dec - 01 Jan	LATAM Airlines Group
04 Dec - 11 Dec	Avianca
08 Dec - 14 Dec	Iberia
05 Dec - 08 Dec	Iberia
02 Dec - 14 Dec	LATAM Airlines Group
05 Dec - 15 Dec	Iberia

Also check the deals for one-way flights from Guayaquil to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Cheapest return flights from Guayaquil to Madrid in December from 653€

Return flights