Cheapest one-way flights from Guayaquil to Madrid in December from 377€

AirHint found the following cheapest one-way flights from Guayaquil (GYE) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

10 Dec Spirit Airlines
05 Dec Spirit Airlines
04 Dec Copa
07 Dec Spirit Airlines
15 Dec Avianca
07 Dec Air Europa direct
22 Dec Avianca
10 Dec Air Europa direct
05 Dec Air Europa direct
21 Dec Air Europa direct

Also check the deals for return flights from Guayaquil to Madrid in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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