AirHint found the following cheapest return flights from Amsterdam (AMS) to Panama City (PTY) in December 2025 (see full year).

Return flights

04 Dec - 23 Dec	United
31 Dec - 22 Jan	United
31 Dec - 23 Jan	United
07 Dec - 15 Dec	United
07 Dec - 08 Dec	Air Europa
15 Dec - 30 Dec	United
15 Dec - 09 Jan	United
13 Dec - 18 Jan	United
12 Dec - 09 Jan	United
14 Dec - 28 Dec	United
14 Dec - 29 Dec	United
14 Dec - 30 Dec	United
31 Dec - 21 Jan	United
31 Dec - 25 Jan	United
14 Dec - 09 Jan	United
31 Dec - 24 Jan	United
01 Dec - 24 Dec	Air Europa
25 Dec - 23 Jan	United
13 Dec - 29 Dec	United
13 Dec - 24 Dec	United

Also check the deals for one-way flights from Amsterdam to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Panama City in December from 565€

Return flights