AirHint found the following cheapest return flights from Amsterdam (AMS) to Panama City (PTY) in December 2025 (see full year).

Return flights

13 Dec - 24 Dec	United
30 Dec - 25 Jan	United
15 Dec - 13 Jan	United
07 Dec - 15 Dec	United
31 Dec - 17 Jan	Air Europa
31 Dec - 18 Jan	Air Europa
05 Dec - 23 Dec	United
04 Dec - 23 Dec	United
13 Dec - 22 Dec	United
29 Dec - 23 Jan	United
12 Dec - 09 Jan	United
31 Dec - 19 Jan	United
25 Dec - 18 Jan	United
29 Dec - 08 Jan	United
29 Dec - 05 Jan	United
24 Dec - 31 Dec	United
01 Dec - 10 Dec	KLM
05 Dec - 23 Dec	KLM	direct
04 Dec - 23 Dec	KLM	direct
18 Dec - 27 Dec	United

Also check the deals for one-way flights from Amsterdam to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Panama City in December from 569€

Return flights