AirHint found the following cheapest return flights from Amsterdam (AMS) to Panama City (PTY) in December 2025 (see full year).

Return flights

07 Dec - 15 Dec	United
04 Dec - 18 Dec	United
06 Dec - 30 Dec	United
06 Dec - 31 Dec	United
05 Dec - 30 Dec	United
13 Dec - 27 Dec	United
30 Dec - 09 Jan	United
15 Dec - 22 Dec	United
26 Dec - 13 Jan	United
25 Dec - 16 Jan	United
25 Dec - 31 Jan	United
29 Dec - 19 Jan	United
25 Dec - 08 Jan	United
28 Dec - 11 Jan	United
28 Dec - 10 Jan	United
25 Dec - 07 Jan	United
14 Dec - 26 Dec	United
13 Dec - 06 Jan	United
19 Dec - 25 Dec	United
22 Dec - 29 Dec	United

Also check the deals for one-way flights from Amsterdam to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Panama City in December from 570€

Return flights