Cheapest one-way flights from Amsterdam to Panama City in December from 454€

AirHint found the following cheapest one-way flights from Amsterdam (AMS) to Panama City (PTY) in December 2025 (see full year).

One-Way flights

13 Dec Ryanair
10 Dec Vueling Airlines
09 Dec TUI.nl
31 Dec Vueling Airlines
01 Dec Air Europa
11 Dec Air Europa
03 Dec Air Europa
16 Dec Vueling Airlines
24 Dec Vueling Airlines
27 Dec Vueling Airlines

Also check the deals for return flights from Amsterdam to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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