Cheapest one-way flights from Santiago to Panama City in December from 337€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Panama City (PTY) in December 2025 (see full year).

One-Way flights

26 Dec Avianca

Also check the deals for return flights from Santiago to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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