Cheapest one-way flights from Santiago to Madrid in September from 376€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

20 Sep Avianca
25 Sep Avianca
23 Sep Avianca
22 Sep Avianca
29 Sep Avianca
28 Sep Avianca
24 Sep LATAM Airlines Group
30 Sep LATAM Airlines Group
27 Sep Avianca
21 Sep LATAM Airlines Group

Also check the deals for return flights from Santiago to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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