Cheapest one-way flights from Santiago to Madrid in September from 371€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

30 Sep LATAM Airlines Group
23 Sep LATAM Airlines Group
25 Sep LATAM Airlines Group
26 Sep LATAM Airlines Group
22 Sep LATAM Airlines Group
24 Sep LATAM Airlines Group
29 Sep Avianca
20 Sep LATAM Airlines Group
27 Sep LATAM Airlines Group
06 Sep LATAM Airlines Group

Also check the deals for return flights from Santiago to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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