AirHint found the following cheapest one-way flights from Panama City (PTY) to Mexico City (MEX) in December 2025 (see full year).
One-Way flights
| 25 Dec | Aeromexico | direct | |
| 24 Dec | Aeromexico | direct | |
| 30 Dec | Copa | direct | |
| 31 Dec | Copa | direct | |
| 15 Dec | Avianca | ||
| 13 Dec | Avianca | ||
| 10 Dec | Avianca | ||
| 11 Dec | Avianca | ||
| 14 Dec | Avianca | ||
| 27 Dec | Avianca |
Also check the deals for return flights from Panama City to Mexico City in December.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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