Cheapest one-way flights from Rio Negro to Madrid in September from 331€

AirHint found the following cheapest one-way flights from Rio Negro (MDE) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

13 Sep Spirit Airlines
26 Sep Spirit Airlines
20 Sep Spirit Airlines
23 Sep Spirit Airlines
25 Sep Avianca
28 Sep Spirit Airlines
21 Sep Spirit Airlines
29 Sep Spirit Airlines
22 Sep Spirit Airlines
15 Sep Spirit Airlines

Also check the deals for return flights from Rio Negro to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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