Cheapest one-way flights from Madrid to Panama City in August from 459€

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Panama City (PTY) in August 2025 (see full year).

One-Way flights

16 Aug Avianca
12 Aug Avianca
13 Aug Avianca
09 Aug Plus Ultra Lineas Aereas
11 Aug Plus Ultra Lineas Aereas
16 Aug Air Europa direct
02 Aug Iberia
07 Aug Ryanair
04 Aug Avianca
11 Aug Air Europa direct

Also check the deals for return flights from Madrid to Panama City in August.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City