Cheapest one-way flights from Madrid to Panama City in April from 280€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Panama City (PTY) in April 2026 (see full year).

One-Way flights

17 Apr Air Europa direct
15 Apr Ryanair
25 Apr Air Europa direct
16 Apr Air Europa direct
05 Apr Wizz Air Malta
21 Apr Air Europa direct
22 Apr Air Europa direct
19 Apr Air Europa direct
27 Apr Air Europa direct
06 Apr Wizz Air Malta

Also check the deals for return flights from Madrid to Panama City in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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