Cheapest one-way flights from Madrid to Panama City in April from 380€

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Panama City (PTY) in April 2025 (see full year).

One-Way flights

02 Apr Air Europa direct
05 Apr Air Europa direct
21 Apr Air Europa direct
27 Apr Air Europa direct
14 Apr Air Europa direct
01 Apr Air Europa direct
08 Apr Air Europa direct
23 Apr Air Europa direct
22 Apr Air Europa direct
07 Apr Air Europa direct

Also check the deals for return flights from Madrid to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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